Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332028 | 0.81 | AKR1B1 (0.52) | SRD5A2FFAR1AKR1B1 | |
| SCHEMBL32660768 | 0.79 | SLC6A2 (0.58) | SLC6A9SRD5A2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25033296 | 0.77 | SRD5A2 (0.57) | SRD5A2FFAR1ALOX15AKR1B1ABCC4 | |
| SCHEMBL6976977 | 0.76 | FFAR1 (0.43) | SLC6A9SRD5A2SLC6A4FFAR1ALOX15 | |
| SCHEMBL32660758 | 0.76 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL32660765 | 0.76 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL32660760 | 0.76 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL4565148 | 0.75 | FFAR1 (0.73) | SRD5A2FFAR1AKR1B1 | |
| SCHEMBL11490486 | 0.75 | SRD5A2 (0.50) | SRD5A2FFAR1ALOX15AKR1B1ABCC4 | |
| SCHEMBL27662594 | 0.75 | FFAR1 (0.73) | SRD5A2FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |