Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.68 |
| ▸ | STAT3 | P40763 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671288 | 0.82 | CTSD (0.70) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL353828 | 0.82 | CTSD (0.70) | CTSDSTAT3RAB9ANPC1POLB | |
| SCHEMBL528651 | 0.81 | CTSD (0.68) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL295407 | 0.81 | CTSD (1.00) | CTSDSTAT3RAB9ANPC1POLB | |
| Hydrochloric Acid SCHEMBL7476155 | 0.81 | CTSD (0.68) | CTSDSTAT3RAB9ANPC1POLB | |
| SCHEMBL13527481 | 0.81 | CTSD (0.73) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3927357 | 0.81 | CTSD (0.68) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6504497 | 0.81 | CTSD (0.68) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31097029 | 0.81 | CTSD (0.68) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30349208 | 0.81 | CTSD (1.00) | CTSDSTAT3RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019177-A1 | AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| WO-2005019177-A1 | AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |