Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.63 |
| ▸ | PPARA | Q07869 | 11/20 | 0.63 |
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234859 | 0.91 | PPARD (0.59) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL6237463 | 0.91 | PPARD (0.63) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL6239835 | 0.91 | PPARD (0.66) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL6242977 | 0.89 | PPARD (0.61) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL2167820 | 0.89 | PPARD (0.81) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL6259683 | 0.86 | PPARD (0.62) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL6236335 | 0.85 | PPARD (0.70) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL6242533 | 0.84 | PPARD (0.74) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL4806106 | 0.83 | PPARD (0.78) | PPARDPPARAPPARGMAPTMEN1 | |
| SCHEMBL6235696 | 0.81 | PPARD (0.64) | PPARDPPARAPPARGMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189895-B1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2005-06-08 | — | — | EP | claimed |