Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | DRD4 | P21917 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005072 | 0.78 | DRD2 (0.47) | DRD2DRD4DRD3HTR1AKCNH2 | |
| SCHEMBL4010998 | 0.77 | DRD4 (0.53) | DRD2DRD4DRD3HTR1APOLB | |
| SCHEMBL4000373 | 0.72 | DRD2 (0.60) | DRD2DRD4DRD3HTR1ALMNA | |
| SCHEMBL4003835 | 0.70 | DRD4 (0.64) | DRD2DRD4DRD3HTR1ALMNA | |
| SCHEMBL4005802 | 0.69 | DRD4 (0.54) | DRD2DRD4DRD3HTR1ALMNA | |
| SCHEMBL6349909 | 0.69 | DRD4 (0.46) | DRD2DRD4 | |
| SCHEMBL6246218 | 0.69 | POLB (0.41) | POLBCHRM3ALDH1A1 | |
| SCHEMBL4007453 | 0.68 | DRD4 (0.52) | DRD2DRD4DRD3HTR1ALMNA | |
| SCHEMBL4007653 | 0.68 | DRD4 (0.61) | DRD2DRD4DRD3HTR1ALMNA | |
| SCHEMBL4003584 | 0.68 | DRD4 (0.51) | DRD2DRD4DRD3HTR1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |