Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.54 |
| ▸ | PPARA | Q07869 | 12/20 | 0.54 |
| ▸ | PPARG | P37231 | 8/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242514 | 0.89 | PPARD (0.54) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL6240400 | 0.79 | PPARD (0.51) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL6500900 | 0.77 | PPARD (0.52) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL15160329 | 0.76 | PPARD (0.61) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL5016708 | 0.76 | PPARD (0.52) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6237739 | 0.76 | PPARD (0.56) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL6263799 | 0.75 | PPARD (0.59) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL4677332 | 0.74 | PPARD (0.56) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL15158746 | 0.74 | PPARD (0.58) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL6237277 | 0.74 | PPARD (0.72) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189895-B1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2005-06-08 | — | — | EP | claimed |