Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.58 |
| ▸ | PPARA | Q07869 | 13/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237810 | 0.84 | PPARD (0.83) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6497059 | 0.81 | PPARD (0.50) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6500781 | 0.81 | PPARD (0.51) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6495846 | 0.81 | FFAR1 (0.48) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6495570 | 0.81 | PPARD (0.51) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6236710 | 0.79 | PPARD (0.81) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6240042 | 0.79 | PPARD (0.59) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL27621737 | 0.78 | PPARD (0.69) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL4860828 | 0.78 | FFAR1 (0.65) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6241282 | 0.78 | PPARD (0.61) | PPARDFFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189895-B8 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1189895-A1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | GLAXO GROUP LIMITED (GB) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000603-A1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | GLAXO GROUP LIMITED (GB) | 2001-01-04 | — | — | WO | disclosed |