Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.64 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046391 | 0.91 | CTSK (0.65) | CTSKCTSSCCR1POLBCTSL | |
| SCHEMBL4038905 | 0.91 | CTSK (0.67) | CTSKCTSSCCR1POLBCTSL | |
| SCHEMBL4039964 | 0.90 | CTSK (0.64) | CTSKCTSSCCR1POLBCTSL | |
| SCHEMBL4045530 | 0.90 | CTSK (0.64) | CTSKCTSSCCR1CTSLCTSV | |
| SCHEMBL4042142 | 0.90 | CTSK (0.66) | CTSKCTSSCCR1POLBCTSL | |
| SCHEMBL4042339 | 0.89 | CTSK (0.63) | CTSKCTSSCCR1POLBCTSL | |
| SCHEMBL4040949 | 0.89 | CTSK (0.65) | CTSKCTSSCCR1POLBCTSL | |
| SCHEMBL4043986 | 0.89 | CTSK (0.62) | CTSKCTSSCCR1POLBCA12 | |
| SCHEMBL4042359 | 0.88 | CTSK (0.64) | CTSKCTSSCCR1POLBCTSL | |
| SCHEMBL4041035 | 0.88 | CTSK (0.64) | CTSKCTSSCCR1CTSLCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |