Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241438 | 0.92 | ADRB1 (0.39) | ADRB1ADRB3SCN9ASCN5AMEN1 | |
| SCHEMBL6242734 | 0.89 | ADRB1 (0.40) | ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL4468034 | 0.80 | ADRB3 (0.46) | ADRB1ADRB3SCN9ASCN5AROCK2 | |
| SCHEMBL4478505 | 0.79 | ADRB3 (0.47) | ADRB1ADRB3SCN9ASCN5AROCK2 | |
| SCHEMBL6242949 | 0.77 | ADRB3 (0.54) | ADRB1ADRB3 | |
| SCHEMBL6245004 | 0.75 | ADRB3 (0.49) | ADRB1ADRB3 | |
| SCHEMBL6238758 | 0.75 | ADRB3 (0.51) | ADRB1ADRB3PTAFR | |
| SCHEMBL6240879 | 0.74 | ADRB3 (0.55) | ADRB1ADRB3ROCK2ROCK1 | |
| SCHEMBL6243377 | 0.73 | ADRB1 (0.42) | ADRB1ADRB3 | |
| SCHEMBL4458979 | 0.73 | ADRB1 (0.38) | ADRB1ADRB3SCN9ASCN5AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546086-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004002939-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | WO | disclosed |