Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239551 | 1.00 | SLC7A5 (0.46) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL5795472 | 0.84 | SLC7A5 (0.46) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL5795467 | 0.84 | SLC7A5 (0.46) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL5280033 | 0.81 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL8697806 | 0.81 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL8701267 | 0.81 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL8701275 | 0.81 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL5795469 | 0.78 | SLC7A5 (0.46) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL7535154 | 0.78 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL2815963 | 0.78 | GABRR1 (0.57) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009471-A1 | COMPOSITION FOR LOWERING BLOOD-SUGAR LEVEL | OSAKA INDUSTRIAL PROMOTION ORGANIZATION (JP) | 2005-02-03 | — | — | WO | disclosed |