Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701267 | 1.00 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL6239551 | 0.81 | SLC7A5 (0.46) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL6239556 | 0.81 | SLC7A5 (0.46) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL17002134 | 0.80 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL7535154 | 0.80 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL2815970 | 0.80 | GABRR1 (0.57) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL17293243 | 0.80 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL8701275 | 0.80 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL5280033 | 0.80 | SLC7A5 (0.49) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 | |
| SCHEMBL2815963 | 0.80 | GABRR1 (0.57) | SLC7A5CYP3A4GRIA2GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849695-A | Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0539491-A4 | — | — | 1994-03-23 | — | — | EP | disclosed |
| EP-0539491-A1 | PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992000753-A1 | PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-01-23 | — | — | WO | disclosed |