Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.75 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.62 |
| ▸ | RXRA | P19793 | 3/20 | 0.61 |
| ▸ | RXRB | P28702 | 2/20 | 0.61 |
| ▸ | RXRG | P48443 | 1/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242006 | 0.84 | RXRA (0.63) | SRD5A2RXRARXRBRXRGNR1H2 | |
| SCHEMBL2200766 | 0.80 | SRD5A2 (0.49) | SRD5A2RXRAMAOBMAOANR1H2 | |
| SCHEMBL19951231 | 0.79 | MAOB (0.76) | SRD5A2NR4A2RXRARXRBRXRG | |
| SCHEMBL6525591 | 0.79 | MAOB (0.76) | SRD5A2NR4A2RXRARXRBRXRG | |
| SCHEMBL14014028 | 0.77 | NR4A2 (1.00) | NR4A2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL978743 | 0.76 | MRGPRX4 (0.56) | SRD5A2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL30413540 | 0.76 | MRGPRX4 (0.56) | SRD5A2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL21945026 | 0.76 | SRD5A2 (0.45) | SRD5A2RXRARXRBRXRGMAOB | |
| SCHEMBL956796 | 0.76 | NR1H2 (0.55) | SRD5A2NR4A2RXRARXRBRXRG | |
| SCHEMBL6088493 | 0.76 | MRGPRX4 (0.50) | SRD5A2NR4A2RXRAMRGPRX4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |