⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986595 | 0.96 | — | — | |
| SCHEMBL14562477 | 0.76 | — | — | |
| SCHEMBL302038 | 0.76 | — | — | |
| SCHEMBL2105710 | 0.76 | — | — | |
| SCHEMBL9453381 | 0.71 | — | — | |
| SCHEMBL9130730 | 0.71 | — | — | |
| SCHEMBL12446446 | 0.71 | — | — | |
| SCHEMBL3561 | 0.71 | — | — | |
| SCHEMBL5985489 | 0.71 | — | — | |
| SCHEMBL14562463 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266015-B1 | ECDYSONE RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM | RHEOGENE HOLDINGS INC (US) | 2006-08-30 | — | — | EP | claimed |
| US-6642273-B2 | Dermatology, vision defects, cardiovascular disorders, antiinflammatory | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-11-04 | — | — | US | claimed |
| US-20030191145-A1 | Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-10-09 | — | — | US | claimed |
| US-6534545-B1 | Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-03-18 | — | — | US | claimed |
| EP-0905118-B1 | Unsaturated 6-tert-butyl-1,1-dimethylindane derivates substituted in the 4-position and their use in human and veterinary medicine as well as in cosmetics | GALDERMA RES & DEV (FR) | 2001-08-16 | — | — | EP | claimed |
| US-6180674-B1 | THERAPY FOR SKIN DISORDERS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2001-01-30 | — | — | US | claimed |
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | claimed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | claimed |
| US-12042479-B2 | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders | INMED PHARMACEUTICALS INC. | 2024-07-23 | — | — | US | disclosed |
| US-20240238427-A1 | METHODS OF TREATING AN EYE DISORDER | KODIAK SCIENCES INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239751-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | BRIDGEBIO GENE THERAPY RESEARCH, INC. | 2024-07-18 | — | — | US | disclosed |
| CN-118344348-A | Heterocyclic substituted quinazoline and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20240228480-A1 | PROCESSES FOR PREPARING PYRROLOPYRIDINE-ANILINE COMPOUNDS | CURIA GLOBAL, INC. | 2024-07-11 | — | — | US | disclosed |
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | disclosed |
| US-4762849-A | NONTOXIC | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-09 | — | — | US | disclosed |
| US-4725610-A | TREATMENT OF HYPERLIPEMIA AND DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0219111-A2 | Cardiotonic alkanoylthiazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-22 | — | — | EP | disclosed |
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| US-4340607-A | Antimicrobial 3H-naphtho[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-07-20 | — | — | US | disclosed |