Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239739 | 1.00 | EGFR (0.52) | EGFRBACE1PTPN1TSHRALDH1A1 | |
| SCHEMBL7770411 | 0.89 | SLC6A4 (0.55) | EGFRBACE1PTPN1ALDH1A1NPC1 | |
| SCHEMBL7770408 | 0.89 | SLC6A4 (0.55) | EGFRBACE1PTPN1ALDH1A1NPC1 | |
| SCHEMBL7770404 | 0.88 | EGFR (0.47) | EGFRBACE1PTPN1TSHRALDH1A1 | |
| SCHEMBL7774818 | 0.85 | PTPN1 (0.49) | EGFRPTPN1TSHRALDH1A1NPC1 | |
| SCHEMBL7774820 | 0.85 | PTPN1 (0.49) | EGFRPTPN1TSHRALDH1A1NPC1 | |
| SCHEMBL7532835 | 0.85 | EGFR (0.60) | EGFRPTPN1TSHRALDH1A1NPC1 | |
| SCHEMBL7532838 | 0.85 | EGFR (0.60) | EGFRPTPN1TSHRALDH1A1NPC1 | |
| SCHEMBL7774938 | 0.84 | BACE1 (0.58) | EGFRBACE1PTPN1ALDH1A1NPC1 | |
| SCHEMBL7774941 | 0.84 | BACE1 (0.58) | EGFRBACE1PTPN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |