SCHEMBL7532835

SCHEMBL7532835

COC(=O)c1ccc(/C=C/c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.60
TSHR P16473 1/20 0.60
PTPN1 P18031 2/20 0.59
ALDH1A1 P00352 2/20 0.58
PDCD1 Q15116 1/20 0.57
CD274 Q9NZQ7 1/20 0.57
RAB9A P51151 3/20 0.54
NPC1 O15118 3/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
MAPT P10636 3/20 0.53
HDAC2 Q92769 2/20 0.53
CASP3 P42574 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7532838 1.00 EGFR (0.60) EGFRTSHRPTPN1ALDH1A1PDCD1
SCHEMBL521422 0.91 TSHR (0.67) TSHRPTPN1ALDH1A1RAB9ANPC1
SCHEMBL521421 0.91 TSHR (0.67) TSHRPTPN1ALDH1A1RAB9ANPC1
SCHEMBL13899905 0.90 TSHR (0.56) EGFRTSHRPTPN1ALDH1A1PDCD1
SCHEMBL1105491 0.89 TSHR (0.75) EGFRTSHRPTPN1ALDH1A1PDCD1
SCHEMBL2363454 0.89 EGFR (0.57) EGFRTSHRPTPN1ALDH1A1PDCD1
Phosphine SCHEMBL28493400 0.87 TSHR (0.72) EGFRTSHRPTPN1ALDH1A1PDCD1
Phosphine SCHEMBL28496548 0.87 TSHR (0.72) EGFRTSHRPTPN1ALDH1A1PDCD1
SCHEMBL71402 0.87 PTPN1 (0.73) TSHRPTPN1ALDH1A1RAB9ANPC1
SCHEMBL71401 0.87 PTPN1 (0.73) TSHRPTPN1ALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868466-B1 SOIL RELEASE POLYMERS WITH FLUORESCENT WHITENING PROPERTIES PROCTER & GAMBLE (US) 2002-04-03 EP disclosed
WO-1998059030-A1 SOIL RELEASE POLYMERS WITH FLUORESCENT WHITENING PROPERTIES THE PROCTER & GAMBLE COMPANY (US) 1998-12-30 WO disclosed
US-5834412-A POLYETHYLENE TEREPHTHALATE COMPRISING FLUORESCENT WHITENING GROUPS THE PROCTER & GAMBLE COMPANY (US) 1998-11-10 US disclosed
US-5728671-A OLIGOMERS, POLYESTERS WITH FLUORESCENT WHITENING GROUPS FOR SOILS RELEASE THE PROCTER & GAMBLE COMPANY (US) 1998-03-17 US disclosed