Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | MDM4 | O15151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451314 | 0.89 | KMT2A (0.57) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL13218997 | 0.88 | CASP3 (0.54) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL2625076 | 0.87 | KMT2A (0.58) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL25002346 | 0.86 | CASP3 (0.56) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL3267363 | 0.86 | KMT2A (0.54) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL12681450 | 0.86 | CASP3 (0.56) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL7743458 | 0.85 | KMT2A (0.57) | KMT2ACASP3EPHX2 | |
| SCHEMBL1486191 | 0.85 | CASP3 (0.54) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL7390390 | 0.85 | CASP3 (0.52) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL2551441 | 0.85 | CASP3 (0.54) | KMT2ACASP3EPHX2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1543019-A2 | MODIFIED PNA MOLECULES | Santaris Pharma A/S (DK) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004024757-A2 | MODIFIED PNA MOLECULES | SANTARIS PHARMA A/S (DK) | 2004-03-25 | — | — | WO | disclosed |