Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.61 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19372016 | 0.88 | UBE2T (0.70) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL5154626 | 0.85 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL29406561 | 0.85 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL244156 | 0.84 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL9641726 | 0.84 | SMN1; SMN2 (0.70) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL3529770 | 0.81 | UBE2T (0.72) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL8904885 | 0.81 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL12511 | 0.81 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL9393861 | 0.81 | UBE2T (0.67) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL3919004 | 0.81 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872930-A | N-substituted 3,4-dihydroisoquinoline-1 (2H) -ketone derivative, composition thereof and application thereof in medicines | 贵州医科大学 | 2023-03-31 | — | — | CN | claimed |
| CN-115872930-A | N-substituted 3,4-dihydroisoquinoline-1 (2H) -ketone derivative, composition thereof and application thereof in medicines | 贵州医科大学 | 2023-03-31 | — | — | CN | disclosed |
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |