SCHEMBL12511

SCHEMBL12511

CCCc1nc2ccccc2s1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBE2T Q9NPD8 1/20 0.61
ASIC3 Q9UHC3 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.57
ALOX15 P16050 1/20 0.57
HTT P42858 1/20 0.57
PDE10A Q9Y233 1/20 0.57
HPGD P15428 5/20 0.55
RAB9A P51151 4/20 0.55
CYP1A2 P05177 3/20 0.54
CYP2C19 P33261 3/20 0.54
KDM4E B2RXH2 3/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2C9 P11712 2/20 0.54
HIF1A Q16665 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
NPC1 O15118 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPK1 P28482 1/20 0.53
GAA P10253 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL23045115 0.98 UBE2T (0.59) UBE2TASIC3SMN1; SMN2ALOX15HTT
Iodide SCHEMBL9106979 0.98 UBE2T (0.59) UBE2TASIC3SMN1; SMN2ALOX15HTT
SCHEMBL2034241 0.89 SMN1; SMN2 (0.62) UBE2TASIC3SMN1; SMN2ALOX15HTT
SCHEMBL19372016 0.88 UBE2T (0.70) UBE2TASIC3SMN1; SMN2ALOX15HTT
SCHEMBL31173766 0.87 ALOX15 (0.60) UBE2TASIC3SMN1; SMN2ALOX15HTT
SCHEMBL175532 0.87 ALOX15 (0.60) UBE2TASIC3SMN1; SMN2ALOX15HTT
Benzene SCHEMBL28273759 0.87 SMN1; SMN2 (0.65) UBE2TASIC3SMN1; SMN2ALOX15HTT
SCHEMBL11596488 0.86 ALOX15 (0.59) UBE2TASIC3SMN1; SMN2ALOX15HTT
SCHEMBL9155744 0.86 ALOX15 (0.59) UBE2TASIC3SMN1; SMN2ALOX15HTT
Hydrochloric Acid SCHEMBL3192243 0.86 ALOX15 (0.59) UBE2TASIC3SMN1; SMN2ALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707859-A Para-substituted heptamethine quinone cyanine dye and synthetic method and application thereof 大连理工大学 2025-03-28 CN claimed
CN-113980583-A Ultraviolet curing composition glue based on pyridine substituted acrylate compound and using method and application thereof 西安思摩威新材料有限公司 2022-01-28 CN claimed
CN-119707859-A Para-substituted heptamethine quinone cyanine dye and synthetic method and application thereof 大连理工大学 2025-03-28 CN disclosed
US-20240294821-A1 CORROSION INHIBITION COMPOSITIONS AND METHODS OF USE IN SOUR ENVIRONMENTS SAUDI ARABIAN OIL COMPANY (SA) 2024-09-05 US disclosed
CN-117024372-A Synthesis method of benzothiazoline 温州大学新材料与产业技术研究院 2023-11-10 CN disclosed
CN-113980583-B Ultraviolet light curing composition glue based on pyridine substituted acrylate compound, and use method and application thereof 西安思摩威新材料有限公司 2023-09-08 CN disclosed
CN-115504942-A Synthesis method of alkyl or acyl substituted benzothiazole derivative 汕头大学 2022-12-23 CN disclosed
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 US disclosed
CN-113980583-A Ultraviolet curing composition glue based on pyridine substituted acrylate compound and using method and application thereof 西安思摩威新材料有限公司 2022-01-28 CN disclosed
CN-113461617-A Method for preparing N-heterocycle through visible light mediated dehydrogenation 石河子大学 2021-10-01 CN disclosed
EP-3835322-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2021-06-16 EP disclosed
US-20120010192-A1 Fused Heterocyclic Compounds as Ion Channel Modulators GILEAD SCIENCES, INC. 2012-01-12 US disclosed
US-20110144090-A1 COMPOUNDS AND METHODS OF USE THEREOF GALENEA CORPORATION 2011-06-16 US disclosed
WO-2011058149-A1 TRICYCLIC PYRAZOL AMINE DERIVATIVES MERCK SERONO S.A. (CH) 2011-05-19 WO disclosed
US-20090036438-A1 FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2009-02-05 US disclosed
US-7453002-B2 thrombotic or an inflammatory disorders; improved factor XIa and/or plasma kallikrein inhibitory activity and selectivity, dosage requirment, costs or feasibility, side effect reduction; 4-(aminomethyl)-N-[2-phenyl-1-(4-pyridin-2-yl-1H-imidazol-2-yl)ethyl]-trans-cyclohexanecarboxamide BRISTOL-MYERS SQUIBB COMPANY (US) 2008-11-18 US disclosed
US-4708810-A LUBRICANT ADDITIVE CASTROL LIMITED (GB) 1987-11-24 US disclosed
EP-0022326-B1 PROCESS FOR CHEMICALLY REMOVING THE ACYL SIDECHAIN FROM CEPHALOSPORINS AND PENICILLINS E.R. Squibb & Sons, Inc. (US) 1983-01-19 EP disclosed
US-4252973-A Process for chemically removing the acyl sidechain from cephalosporins and penicillins E. R. SQUIBB & SONS, INC. (US) 1981-02-24 US disclosed
EP-0022326-A1 Process for chemically removing the acyl sidechain from cephalosporins and penicillins E.R. Squibb & Sons, Inc. (US) 1981-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010192-A1 Fused Heterocyclic Compounds as Ion Channel Modulators KCNJ2, KCNH2, CACNA1E UBE2T 4167/4885ASIC3 150/4885SMN1; SMN2 1093/4885
US-20110144090-A1 COMPOUNDS AND METHODS OF USE THEREOF AANAT, HNMT, INMT UBE2T 3854/4885ASIC3 4370/4885SMN1; SMN2 1404/4885
US-11279733-B2 Peptide antibiotics NGLY1, VIP, PEPD UBE2T 3517/4885ASIC3 2928/4885SMN1; SMN2 4207/4885
US-20090036438-A1 FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS F12, F11, F5 UBE2T 3012/4885ASIC3 1569/4885SMN1; SMN2 4322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.