Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25921416 | 0.73 | MAPT (0.46) | LMNASMN1; SMN2ALDH1A1MMP13POLB | |
| SCHEMBL25921491 | 0.73 | LMNA (0.41) | LMNARAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL6031811 | 0.71 | LMNA (0.55) | LMNARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6244192 | 0.71 | LMNA (0.38) | LMNARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6243612 | 0.70 | MAPT (0.41) | LMNARAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL14139588 | 0.70 | LMNA (0.53) | LMNARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL14611612 | 0.69 | LMNA (0.52) | LMNARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL19514710 | 0.69 | LMNA (0.52) | LMNARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL26084833 | 0.69 | LMNA (0.52) | LMNARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL68678 | 0.68 | LMNA (0.59) | LMNARAB9ASMN1; SMN2KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019207-A1 | FUNGICIDAL PYRIMIDINE DERIVATIVES | NIPPON SODA CO. LTD. (JP) | 2005-03-03 | — | — | WO | disclosed |