Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | KRAS | P01116 | 5/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242581 | 0.99 | HINT1 (0.48) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL6242507 | 0.95 | HINT1 (0.50) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL6243042 | 0.90 | HINT1 (0.50) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL14896399 | 0.89 | HINT1 (0.49) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL1919142 | 0.85 | HINT1 (0.59) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL6239885 | 0.83 | HINT1 (0.44) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL1425533 | 0.80 | HINT1 (0.68) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL5347476 | 0.80 | HINT1 (0.68) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL6241925 | 0.80 | HINT1 (0.68) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL1424945 | 0.80 | HINT1 (0.68) | HINT1NT5EPNPGSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223173-B1 | Novel 2'-O-alkyl nucleosides and phosphoramidites processes for the preparation and uses thereof | ISIS PHARMACEUTICALS INC (US) | 2005-07-13 | — | — | EP | disclosed |