Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 10/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242835 | 0.93 | CYP11B1 (0.43) | CYP11B2CYP11B1GRIA2KCNH2PSEN1 | |
| SCHEMBL6246324 | 0.86 | PSEN1 (0.43) | CYP11B2CYP11B1KCNH2PSEN1PSEN2 | |
| SCHEMBL6241141 | 0.85 | CYP11B1 (0.35) | CYP11B2CYP11B1PSEN1PSEN2APH1B | |
| SCHEMBL6237481 | 0.83 | CYP11B1 (0.39) | CYP11B2CYP11B1PSEN1PSEN2APH1B | |
| SCHEMBL6236867 | 0.83 | ADAMTS4 (0.40) | CYP11B2CYP11B1HRH3PGR | |
| SCHEMBL6240184 | 0.82 | CYP11B1 (0.39) | CYP11B2CYP11B1PSEN1PSEN2APH1B | |
| SCHEMBL6241979 | 0.81 | GRIA4 (0.51) | CYP11B2CYP11B1GRIA2KCNH2GRIA4 | |
| SCHEMBL6239570 | 0.81 | ADAMTS4 (0.43) | CYP11B2CYP11B1KCNH2 | |
| SCHEMBL6242093 | 0.79 | CYP11B1 (0.35) | CYP11B2CYP11B1PSEN1PSEN2APH1B | |
| SCHEMBL6244084 | 0.79 | CA12 (0.38) | CYP11B2CYP11B1KCNH2PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395550-B1 | CYCLOALKENYLSULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20040157817-A1 | Cycloalkenylsulfonamide derivatives | CANTELL BUDDY EUGENE (US) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157817-A1 | Cycloalkenylsulfonamide derivatives | GRIN2B, GRIN2A, GRIN1 | CYP11B2 339/4885CYP11B1 444/4885GRIA2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.