Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | IKBKB | O14920 | 5/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.58 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.58 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.58 |
| ▸ | RAF1 | P04049 | 3/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.58 |
| ▸ | AKT1 | P31749 | 3/20 | 0.58 |
| ▸ | AKT2 | P31751 | 3/20 | 0.58 |
| ▸ | KDR | P35968 | 3/20 | 0.58 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.58 |
| ▸ | PRDX1 | Q06830 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593917 | 1.00 | MAPK1 (0.58) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL29487479 | 1.00 | MAPK1 (0.58) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL5593729 | 1.00 | MAPK1 (0.58) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL625689 | 0.97 | MAPK1 (0.58) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL12948680 | 0.84 | MAPK1 (0.70) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL26246396 | 0.76 | MAPT (0.51) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL28054895 | 0.76 | NPC1 (0.54) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL17017319 | 0.76 | ALDH1A1 (0.44) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL3438483 | 0.75 | ALDH1A1 (0.44) | MIFNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL16311079 | 0.75 | MIF (0.57) | MAPK1IKBKBPRKAG1PRKAA1NEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2007072089-A1 | MGLUR5 ANTAGONISTIC CARBAMOYL-OXIME DERIVATIVES | RICHTER GEDEON VEGYÉSZETU GYÁR RT. (HU) | 2007-06-28 | — | — | WO | disclosed |