Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 6/20 | 0.70 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.50 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL20163257 | 1.00 | BDKRB2 (0.70) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| Bromide SCHEMBL5092800 | 1.00 | BDKRB2 (0.70) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| SCHEMBL29570302 | 0.98 | BDKRB2 (0.67) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| Bromide SCHEMBL5087978 | 0.98 | BDKRB2 (0.72) | BDKRB2DNM1CSNK1EKCNH2 | |
| Hydrochloric Acid SCHEMBL28445004 | 0.96 | BDKRB2 (0.70) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL5088466 | 0.96 | BDKRB2 (0.70) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL20163267 | 0.96 | BDKRB2 (0.70) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL624934 | 0.96 | BDKRB2 (0.70) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| Iodide SCHEMBL5085386 | 0.96 | BDKRB2 (0.65) | BDKRB2DNM1CSNK1EKCNH2MEN1 | |
| Bromide SCHEMBL5087781 | 0.96 | BDKRB2 (0.65) | BDKRB2DNM1CSNK1EKCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005524748-A | — | — | 2005-08-18 | — | — | JP | claimed |
| US-6852417-B2 | Composition for improving adhesion of base-resistant fluoroelastomers to metal, ceramic or glass substrates | DUPONT DOW ELASTOMERS, LLC (US) | 2005-02-08 | — | — | US | claimed |
| EP-1501887-A1 | COMPOSITION FOR IMPROVING ADHESION OF BASE-RESISTANT FLUOROELASTOMERS TO METAL, CERAMIC OR GLASS SUBSTRATES | DUPONT DOW ELASTOMERS L.L.C. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20030225189-A1 | Composition for improving adhesion of base-resistant fluoroelastomers to metal, ceramic or glass substrates | DUPONT DOW ELASTOMERS LLC | 2003-12-04 | — | — | US | claimed |
| WO-2003095535-A1 | COMPOSITION FOR IMPROVING ADHESION OF BASE-RESISTANT FLUOROELASTOMERS TO METAL, CERAMIC OR GLASS SUBSTRATES | DUPONT DOW ELASTOMERS L.L.C. (US) | 2003-11-20 | — | — | WO | claimed |
| US-4758618-A | Curable composition of elastomeric vinylidene fluoride copolymer | ASAHI GLASS COMPANY, LTD. (JP) | 1988-07-19 | — | — | US | claimed |
| US-20260098005-A1 | NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | THE CHEMOURS COMPANY FC, LLC (US) | 2026-04-09 | — | — | US | disclosed |
| EP-4602105-A1 | CURABLE FLUOROELASTOMER COMPOSITIONS AND LOW-FRICTION CURED FLUOROELASTOMERS (FKM) FORMED THEREFROM | The Chemours Company FC, LLC (US) | 2025-08-20 | — | — | EP | disclosed |
| EP-4590761-A1 | NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | The Chemours Company FC, LLC (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4590762-A1 | FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | The Chemours Company FC, LLC (US) | 2025-07-30 | — | — | EP | disclosed |
| CN-120092046-A | Curable fluoroelastomer compositions and low friction cured fluoroelastomers (fkM) formed therefrom | 科慕埃弗西有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119998380-A | Fluorinated resorcinol and hydroquinone analogs as curatives for fluoroelastomers | 科慕埃弗西有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119998379-A | Non-fluorinated resorcinol and hydroquinone analogs as curing agents for fluoroelastomers | 科慕埃弗西有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-0218929-A2 | Curable composition of elastomeric vinylidene fluoride copolymer | ASAHI GLASS COMPANY LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| EP-0127318-B1 | CURABLE FLUOROPOLYMER COMPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0140207-A2 | A process for rapidly curing a brominated fluoroelastomer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4496682-A | TWO-STAGE CURING WITH BISPHENOLS, BISAMINES, QUATERNARY AMMONIUM OR PHOSPHONIUM COMPONENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4489196-A | CONTAINING VULCANIZATION ACCELERATOR, CROSSLINKING AGENT, METAL OXIDE OR HYDROXIDE, AND POLYOL COACCELERATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-18 | — | — | US | disclosed |
| EP-0127484-A2 | Curable fluoropolymer containing aromatic amine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| EP-0127318-A1 | Curable fluoropolymer composition | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098005-A1 | NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | CBR1, NAF1, CBR3 | BDKRB2 2640/4885DNM1 3883/4885CSNK1E 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.