Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.40 |
| ▸ | AKT1 | P31749 | 4/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968274 | 0.96 | AKT1 (0.40) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL969041 | 0.93 | ALOX5 (0.44) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL12919844 | 0.93 | ALOX5 (0.44) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL12919845 | 0.93 | ALOX5 (0.44) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL967402 | 0.92 | AKT1 (0.41) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL967545 | 0.89 | AKT1 (0.39) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL969505 | 0.89 | ALOX5 (0.45) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL968256 | 0.86 | ALOX5 (0.43) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL12919862 | 0.85 | ALOX5 (0.43) | ALOX5AKT1PDPK1PHLPP1ILK | |
| SCHEMBL969104 | 0.82 | AKT1 (0.36) | ALOX5AKT1PDPK1PHLPP1ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033093-A1 | 7,8-BICYCLOALKYL-CHROMAN DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-04-14 | — | — | WO | disclosed |