Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 19/20 | 0.90 |
| ▸ | DHFR | P00374 | 2/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243616 | 0.95 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL3633395 | 0.86 | GHSR (0.81) | GHSRDHFR | |
| SCHEMBL6245988 | 0.85 | GHSR (0.89) | GHSRDHFR | |
| SCHEMBL6401434 | 0.85 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL6247503 | 0.85 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL6242991 | 0.85 | GHSR (0.81) | GHSRDHFR | |
| SCHEMBL3635032 | 0.84 | GHSR (0.81) | GHSRDHFR | |
| SCHEMBL6246829 | 0.84 | GHSR (0.63) | GHSRDHFRCNR1 | |
| SCHEMBL6243582 | 0.84 | GHSR (0.83) | GHSRDHFR | |
| SCHEMBL6406692 | 0.84 | GHSR (0.80) | GHSRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | claimed |