Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813736 | 0.83 | CHEK1 (0.78) | CHEK1 | |
| SCHEMBL4810532 | 0.78 | CHEK1 (0.75) | CHEK1 | |
| SCHEMBL6783261 | 0.77 | CHEK1 (0.78) | CHEK1KDR | |
| SCHEMBL4815710 | 0.73 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL4807037 | 0.73 | CHEK1 (0.84) | CHEK1 | |
| SCHEMBL4814833 | 0.72 | CHEK1 (0.70) | CHEK1KDR | |
| SCHEMBL4808045 | 0.72 | CHEK1 (0.55) | CHEK1KDR | |
| SCHEMBL6794435 | 0.71 | CHEK1 (0.74) | CHEK1KDR | |
| SCHEMBL6197873 | 0.70 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL6244607 | 0.69 | CHEK1 (0.63) | CHEK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603885-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-14 | — | — | EP | claimed |
| WO-2004080973-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-23 | — | — | WO | claimed |