Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 0.74 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247733 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL6246046 | 0.83 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL6249064 | 0.82 | MTNR1A (0.87) | MTNR1AMTNR1BHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL8063690 | 0.82 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL6247433 | 0.82 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL6247009 | 0.82 | MTNR1A (0.85) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL6246645 | 0.82 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL6248644 | 0.81 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL5929462 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL6246656 | 0.80 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919541-B1 | Naphthalene compounds, process for their preparation and their pharmaceutical compositions | SERVIER LAB (FR) | 2005-08-10 | — | — | EP | disclosed |
| US-6143789-A | ENANTIOMORPHS | ADIR ET COMPAGNIE (FR) | 2000-11-07 | — | — | US | disclosed |
| EP-0919541-A1 | Naphthalene compounds, process for their preparation and their pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 1999-06-02 | — | — | EP | disclosed |