Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621779 | 0.78 | SHBG (0.65) | SHBG | |
| SCHEMBL11621787 | 0.78 | SHBG (0.65) | SHBG | |
| SCHEMBL6244368 | 0.75 | SHBG (0.37) | SHBGCYP19A1MBOAT4 | |
| SCHEMBL8331556 | 0.70 | SRD5A1 (0.54) | SHBGCYP19A1MBOAT4 | |
| SCHEMBL13047225 | 0.70 | — | — | |
| SCHEMBL11432636 | 0.70 | CYP19A1 (0.37) | SHBGCYP19A1MBOAT4 | |
| SCHEMBL11432633 | 0.70 | CYP19A1 (0.37) | SHBGCYP19A1MBOAT4 | |
| SCHEMBL9068479 | 0.70 | SHBG (0.46) | SHBGCYP19A1 | |
| SCHEMBL9068480 | 0.70 | SHBG (0.46) | SHBGCYP19A1 | |
| SCHEMBL4318904 | 0.69 | SHBG (0.38) | SHBGCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549292-A2 | PHARMACEUTICAL PREPARATIONS, USE OF SAID PREPARATIONS AND METHOD FOR INCREASING THE BIOAVAILABILITY OF MEDICAMENTS FOR PERORAL ADMINISTRATION | Schering Aktiengesellschaft (DE) | 2005-07-06 | — | — | EP | claimed |
| WO-2004032897-A2 | PHARMACEUTICAL PREPARATIONS, USE OF SAID PREPARATIONS AND METHOD FOR INCREASING THE BIOAVAILABILITY OF MEDICAMENTS FOR PERORAL ADMINISTRATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-04-22 | — | — | WO | claimed |
| EP-1549292-A2 | PHARMACEUTICAL PREPARATIONS, USE OF SAID PREPARATIONS AND METHOD FOR INCREASING THE BIOAVAILABILITY OF MEDICAMENTS FOR PERORAL ADMINISTRATION | Schering Aktiengesellschaft (DE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004032897-A2 | PHARMACEUTICAL PREPARATIONS, USE OF SAID PREPARATIONS AND METHOD FOR INCREASING THE BIOAVAILABILITY OF MEDICAMENTS FOR PERORAL ADMINISTRATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-04-22 | — | — | WO | disclosed |