Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 20/20 | 0.66 |
| ▸ | DHFR | P00374 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246378 | 0.94 | GHSR (0.73) | GHSRDHFR | |
| SCHEMBL6339539 | 0.85 | GHSR (0.72) | GHSRDHFR | |
| SCHEMBL6353346 | 0.84 | GHSR (0.70) | GHSRDHFR | |
| SCHEMBL6248057 | 0.83 | HEXA (0.54) | DHFR | |
| SCHEMBL6342213 | 0.81 | GHSR (0.87) | GHSRDHFR | |
| Bromide SCHEMBL6262008 | 0.81 | HEXA (0.53) | DHFR | |
| SCHEMBL3632627 | 0.81 | GHSR (0.67) | GHSRDHFR | |
| SCHEMBL3632486 | 0.81 | GHSR (0.77) | GHSRDHFR | |
| Bromide SCHEMBL6262003 | 0.80 | HEXA (0.51) | DHFR | |
| SCHEMBL3635041 | 0.80 | GHSR (1.00) | GHSRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |