Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromomethane SCHEMBL931692 | 0.97 | CHRM2 (0.35) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL7086017 | 0.94 | POLB (0.33) | POLBMEN1KMT2AKCNN4ALDH1A1 | |
| Bromomethane SCHEMBL7085436 | 0.91 | PDPK1 (0.32) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL14142466 | 0.81 | CHRM3 (0.34) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL931372 | 0.81 | CHRM2 (0.39) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL3911903 | 0.80 | KCNN4 (0.41) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL14142347 | 0.78 | PDPK1 (0.46) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL543310 | 0.78 | KCNN4 (0.40) | CHRM3CHRM2CHRM1POLBMEN1 | |
| Bromomethane SCHEMBL118164 | 0.78 | CHRM2 (0.39) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL14142417 | 0.78 | LMNA (0.45) | CHRM3MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551792-A1 | NOVEL BETA MIMETICS WITH EXTENDED DURATION OF ACTION, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004033412-A1 | NOVEL BETA MIMETICS WITH EXTENDED DURATION OF ACTION, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-22 | — | — | WO | disclosed |