Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237614 | 1.00 | HDAC1 (0.62) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6239953 | 0.85 | HDAC1 (0.71) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6239949 | 0.85 | HDAC1 (0.71) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6237611 | 0.83 | HDAC1 (0.66) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6237618 | 0.83 | HDAC1 (0.66) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6239617 | 0.79 | HDAC1 (0.79) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6239624 | 0.79 | HDAC1 (0.79) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6240690 | 0.77 | HDAC1 (0.72) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL6240216 | 0.77 | HDAC1 (0.72) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL2208074 | 0.75 | MAPT (0.54) | ALDH1A1MAPK1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | claimed |
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |