Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 7/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582021 | 0.86 | HPGD (0.47) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL9581310 | 0.83 | HPGD (0.44) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL6246540 | 0.82 | HPGD (0.45) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL22699805 | 0.81 | HPGD (0.50) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL6245678 | 0.80 | HPGD (0.42) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL6245031 | 0.79 | HPGD (0.49) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL6244790 | 0.77 | HPGD (0.41) | HPGDPARP1PDPK1KDM5B | |
| SCHEMBL22139827 | 0.73 | HPGD (0.50) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL16465704 | 0.72 | HPGD (0.73) | HPGDPARP1PDPK1ALDH1A1CHEK1 | |
| SCHEMBL8404474 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065202-B1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2005-08-03 | — | — | EP | claimed |
| US-6340757-B1 | SYNTHETIC INTERMEDIATE FOR AMINOPYRIMIDINE DERIVATIVES WHICH ARE USEFUL AS ACARICIDES, FUNGICIDES OR NEMATOCIDES, AND PROCESSES FOR PRODUCING THE SAME. | UBE INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | claimed |
| EP-1065202-A1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2001-01-03 | — | — | EP | claimed |
| EP-1065202-B1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6340757-B1 | SYNTHETIC INTERMEDIATE FOR AMINOPYRIMIDINE DERIVATIVES WHICH ARE USEFUL AS ACARICIDES, FUNGICIDES OR NEMATOCIDES, AND PROCESSES FOR PRODUCING THE SAME. | UBE INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1065202-A1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2001-01-03 | — | — | EP | disclosed |