Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 6/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245678 | 0.91 | HPGD (0.42) | HPGDPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL6246540 | 0.84 | HPGD (0.45) | HPGDPARP1PDPK1KDM5BKDM4E | |
| SCHEMBL6246479 | 0.84 | HPGD (0.40) | HPGDPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL6245235 | 0.77 | HPGD (0.50) | HPGDPARP1PDPK1KDM5B | |
| SCHEMBL9582021 | 0.76 | HPGD (0.47) | HPGDPARP1PDPK1KDM5B | |
| SCHEMBL6243820 | 0.75 | HPGD (0.41) | HPGDPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL9581310 | 0.73 | HPGD (0.44) | HPGDPARP1PDPK1KDM5BGAA | |
| SCHEMBL6246141 | 0.72 | PDE2A (0.32) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL22139827 | 0.67 | HPGD (0.50) | HPGDPARP1PDPK1KDM5B | |
| SCHEMBL22958864 | 0.65 | ADORA2B (0.33) | HPGDXDHADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065202-B1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2005-08-03 | — | — | EP | claimed |
| US-6340757-B1 | SYNTHETIC INTERMEDIATE FOR AMINOPYRIMIDINE DERIVATIVES WHICH ARE USEFUL AS ACARICIDES, FUNGICIDES OR NEMATOCIDES, AND PROCESSES FOR PRODUCING THE SAME. | UBE INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | claimed |
| EP-1065202-A1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2001-01-03 | — | — | EP | claimed |
| EP-1065202-B1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6340757-B1 | SYNTHETIC INTERMEDIATE FOR AMINOPYRIMIDINE DERIVATIVES WHICH ARE USEFUL AS ACARICIDES, FUNGICIDES OR NEMATOCIDES, AND PROCESSES FOR PRODUCING THE SAME. | UBE INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1065202-A1 | 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2001-01-03 | — | — | EP | disclosed |