SCHEMBL6245366

SCHEMBL6245366

CCc1ccccc1COc1ccc(C)[n+]([O-])c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.39
PTPRC P08575 1/20 0.39
PTPN1 P18031 1/20 0.39
ADAM17 P78536 3/20 0.37
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
TMPRSS6 Q8IU80 1/20 0.36
ST14 Q9Y5Y6 1/20 0.36
MMP13 P45452 3/20 0.35
MMP1 P03956 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAOA P21397 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
ACHE P22303 1/20 0.35
FFAR1 O14842 1/20 0.34
PPARG P37231 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL228426 0.80 CA12 (0.49) MAOBL3MBTL1MAOAMAPTHPGD
SCHEMBL16555009 0.78 CD274 (0.54)
SCHEMBL9264667 0.77 NQO1 (0.50) PRSS1PRSS2PRSS3MAPTHPGD
SCHEMBL3332404 0.74 CA12 (0.47) L3MBTL1
SCHEMBL12920460 0.73 PTPRC (0.55) MAOBPTPRCPTPN1F2PRSS1
SCHEMBL13794698 0.71 TDP1 (0.51) MAOBPTPRCPTPN1L3MBTL1ACHE
SCHEMBL11854894 0.70 LTA4H (0.60) MAOBPTPRCPTPN1F2PRSS1
SCHEMBL6244116 0.70 CD274 (0.42) MAOBPTPRCPTPN1MAPT
SCHEMBL3303080 0.69 CYP3A4 (0.44) L3MBTL1MAOAGPR84
SCHEMBL13794364 0.69 MAOB (0.50) MAOBMAOAACHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005033119-A9 SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS UNIV WARWICK (GB) 2005-07-21 WO disclosed
WO-2005033119-A1 SUPRAMOLECULAR COMPOUNDS AND THEIR USE AS ANTITUMOUR AND ANTIVIRAL AGENTS UNIVERSITY OF WARWICK (GB) 2005-04-14 WO disclosed