Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 16/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246583 | 0.89 | HPSE (0.82) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6244234 | 0.87 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6264780 | 0.86 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6265376 | 0.86 | HPSE (0.82) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6263153 | 0.84 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6247745 | 0.83 | HPSE (0.79) | HPSE | |
| SCHEMBL14381770 | 0.82 | COMT (0.66) | HPSEMAPTSMN1; SMN2 | |
| SCHEMBL6244183 | 0.81 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6248635 | 0.80 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6265143 | 0.80 | HPSE (0.80) | HPSEMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030206-A1 | ARYL-1,3-AZOLE DERIVATIVES AND METHODS FOR INHIBITING HEPARNASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |