Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 13/20 | 1.00 |
| ▸ | MMP2 | P08253 | 3/20 | 0.63 |
| ▸ | MMP9 | P14780 | 3/20 | 0.63 |
| ▸ | MMP8 | P22894 | 3/20 | 0.63 |
| ▸ | MMP13 | P45452 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264780 | 0.90 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6244234 | 0.89 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6246583 | 0.87 | HPSE (0.82) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6265376 | 0.87 | HPSE (0.82) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6258786 | 0.85 | HPSE (0.77) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6245492 | 0.84 | HPSE (0.77) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6264637 | 0.83 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B | |
| SCHEMBL6247745 | 0.82 | HPSE (0.79) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6248635 | 0.82 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6266518 | 0.81 | HPSE (1.00) | HPSEMAPTRECQLBLMCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030206-A1 | ARYL-1,3-AZOLE DERIVATIVES AND METHODS FOR INHIBITING HEPARNASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |