Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245804 | 1.00 | PTGDR (0.44) | PTGDRIKBKBEPHX2HRH1CCR3 | |
| SCHEMBL6104724 | 1.00 | PTGDR (0.44) | PTGDRIKBKBEPHX2HRH1CCR3 | |
| SCHEMBL6220281 | 0.92 | EPHX2 (0.41) | PTGDRIKBKBEPHX2UTS2RSCD | |
| SCHEMBL6104086 | 0.83 | PTGDR (0.45) | PTGDRIKBKBHRH1CCR3UTS2R | |
| SCHEMBL6246834 | 0.81 | IKBKB (0.42) | PTGDRIKBKBHRH1CCR3PKM | |
| SCHEMBL6246832 | 0.81 | IKBKB (0.43) | PTGDRIKBKBPKMSCDALDH1A1 | |
| SCHEMBL27604308 | 0.81 | PTGDR (0.43) | PTGDRIKBKBEPHX2HRH1CCR3 | |
| SCHEMBL6103514 | 0.80 | PTGDR (0.41) | PTGDRIKBKBHRH1CCR3UTS2R | |
| SCHEMBL6218902 | 0.77 | PTGDR (0.42) | PTGDRIKBKBUTS2RALDH1A1POLB | |
| SCHEMBL6218839 | 0.77 | PTGDR (0.42) | PTGDRIKBKBUTS2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |