SCHEMBL624583

SCHEMBL624583

CCCCCCCCCCCCCC=Cc1cccc(OCC2CO2)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
TP53 P04637 3/20 0.54
TSHR P16473 3/20 0.54
HIF1A Q16665 2/20 0.54
CYP3A4 P08684 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TDP1 Q9NUW8 2/20 0.44
TLR4 O00206 2/20 0.43
TLR2 O60603 2/20 0.43
PPARA Q07869 2/20 0.41
CYSLTR2 Q9NS75 1/20 0.38
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL624582 1.00 ALDH1A1 (0.54) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL5176201 0.92 ALDH1A1 (0.50) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL5176193 0.92 ALDH1A1 (0.50) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL30690430 0.82 PPARA (0.63) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL22632289 0.82 PPARA (0.63) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL4458552 0.82 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TDP1
SCHEMBL28613839 0.82 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TDP1
SCHEMBL22245451 0.82 ALDH1A1 (0.74) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL22245452 0.82 ALDH1A1 (0.74) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL28979204 0.79 ALDH1A1 (0.66) ALDH1A1TP53TSHRHIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10300005-B2 Personal care composition and methods containing hydrophobically-modified hydroxyethylcellulose UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2019-05-28 US claimed
US-10300005-B2 Personal care composition and methods containing hydrophobically-modified hydroxyethylcellulose UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2019-05-28 US disclosed
EP-2603554-B1 WELLBORE SERVICING FLUID COMPRISING A CELLULOSE ETHER UNION CARBIDE CHEM PLASTIC (US) 2019-03-27 EP disclosed
EP-2760801-B1 CEMENTING COMPOSITION COMPRISING ANIONICALLY - AND HYDROPHOBICALLY-MODIFIED (HYDROXY)ALKYL CELLULOSE ETHERS AND ITS USE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-07 EP disclosed
EP-2726155-B1 PERSONAL CARE COMPOSITION AND METHODS CONTAINING HYDROPHOBICALLY-MODIFIED HYDROXYALKYLCELLULOSE ROHM & HAAS (US) 2017-07-12 EP disclosed
EP-2603532-B1 NONIONIC HYDROPHOBICALLY SUBSTITUTED CELLULOSE ETHERS UNION CARBIDE CHEM PLASTIC (US) 2016-11-30 EP disclosed
US-9266971-B2 Nonionic hydrophobically substituted cellulose ethers DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-23 US disclosed
US-9266969-B2 Wellbore servicing fluid comprising a cellulose ether DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-23 US disclosed
US-20140345867-A1 CEMENTING COMPOSITION COMPRISING ANIONICALLY- AND HYDROPHOBICALLY-MODIFIED CELLULOSE ETHERS AND ITS USE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-27 US disclosed
EP-2760801-A1 CEMENTING COMPOSITION COMPRISING ANIONICALLY - AND HYDROPHOBICALLY-MODIFIED CELLULOSE ETHERS AND ITS USE Dow Global Technologies LLC (US) 2014-08-06 EP disclosed
WO-2013049094-A1 CEMENTING COMPOSITION COMPRISING ANIONICALLY - AND HYDROPHOBICALLY-MODIFIED CELLULOSE ETHERS AND ITS USE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-04 WO disclosed
WO-2012021625-A2 NONIONIC HYDROPHOBICALLY SUBSTITUTED CELLULOSE ETHERS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2012-02-16 WO disclosed
WO-2012021626-A2 WELLBORE SERVICING FLUID COMPRISING A CELLULOSE ETHER UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2012-02-16 WO disclosed
US-20090324958-A1 Heat Setting Compounds Suitable for Sticking Together Coated Substrates SIKA TECHNOLOGY AG (CH) 2009-12-31 US disclosed
EP-1876194-A1 Heat curing composition usable as an adhesive for coated substrates Sika Technology AG (CH) 2008-01-09 EP disclosed
WO-2008000830-A1 HEAT SETTING COMPOUNDS SUITABLE FOR STICKING TOGETHER COATED SUBSTRATES SIKA TECHNOLOGY AG (CH) 2008-01-03 WO disclosed
EP-0718310-B1 Dual functional cellulosic additives for latex compositions UNION CARBIDE CHEM PLASTIC (US) 2001-10-10 EP disclosed
US-5583214-A CELLULOSE ETHER CONTAINING HYDROPHOBIC ALKENE-TYPE SUBSTITUENT; HARDNESS, DURABILITY, THICKENING AND RHEOLOGY MODIFICATION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-12-10 US disclosed
EP-0718310-A2 Dual functional cellulosic additives for latex compositions UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-06-26 EP disclosed
US-5504123-A AQUEOUS MIXTURE WITH THICKENER OF CROSSLINKABLE CELLULOSE ETHER WHICH HAS HYDROPHOBIC ALKENE SUBSTITUENT UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-04-02 US disclosed