Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.47 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 9/20 | 0.43 |
| ▸ | JAK2 | O60674 | 6/20 | 0.42 |
| ▸ | JAK3 | P52333 | 4/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842934 | 0.81 | MEN1 (0.49) | TBK1IKBKEALDH1A1KDM4EGAA | |
| SCHEMBL4834658 | 0.77 | JAK1 (0.52) | TBK1JAK1JAK2JAK3SYK | |
| SCHEMBL22223723 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1GAALMNA | |
| SCHEMBL4842844 | 0.73 | IKBKE (0.45) | TBK1IKBKEALDH1A1KDM4EKMT2A | |
| SCHEMBL4840443 | 0.72 | TBK1 (0.73) | TBK1IKBKEJAK1JAK2JAK3 | |
| SCHEMBL4833993 | 0.72 | TBK1 (0.79) | TBK1IKBKEJAK1JAK2JAK3 | |
| SCHEMBL6248111 | 0.71 | TBK1 (0.65) | TBK1IKBKEJAK1 | |
| SCHEMBL4838835 | 0.70 | TBK1 (0.64) | TBK1IKBKEJAK1ALDH1A1KDM4E | |
| SCHEMBL4838927 | 0.68 | TBK1 (0.58) | TBK1IKBKEALDH1A1KDM4EFLT3 | |
| SCHEMBL4843679 | 0.67 | TBK1 (0.78) | TBK1IKBKEJAK1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-A1 | USE OF AND SOME NOVEL IMIDAZOPYRIDINES | AstraZeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004016611-A1 | USE OF AND SOME NOVEL IMIDAZOPYRIDINES | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | WO | disclosed |