Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248197 | 1.00 | MAPT (0.55) | MAPTCYP1A2MEN1KMT2ALMNA | |
| SCHEMBL6246458 | 1.00 | MAPT (0.55) | MAPTCYP1A2MEN1KMT2ALMNA | |
| SCHEMBL11372184 | 0.83 | MEN1 (0.54) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL11372177 | 0.83 | MEN1 (0.54) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL708213 | 0.76 | MAPT (0.59) | MAPTCYP1A2MEN1KMT2ALMNA | |
| SCHEMBL16115071 | 0.74 | MAPT (0.60) | MAPTCYP1A2MEN1KMT2ALMNA | |
| SCHEMBL2433672 | 0.71 | APP (0.45) | MAPTCYP1A2MEN1KMT2ALMNA | |
| SCHEMBL3218584 | 0.71 | MAPT (1.00) | MAPTCYP1A2MEN1KMT2ALMNA | |
| SCHEMBL386528 | 0.71 | CA12 (0.73) | MAPTCYP1A2MEN1KMT2ALMNA | |
| SCHEMBL386527 | 0.71 | CA12 (0.73) | MAPTCYP1A2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |