Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372177 | 1.00 | MEN1 (0.54) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4340138 | 0.83 | MEN1 (0.51) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6246458 | 0.83 | MAPT (0.55) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL6248197 | 0.83 | MAPT (0.55) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL6246459 | 0.83 | MAPT (0.55) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL6249973 | 0.79 | KMT2A (0.42) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL6249968 | 0.79 | KMT2A (0.42) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL20109332 | 0.76 | MEN1 (0.51) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10918591 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28841505 | 0.75 | MEN1 (0.58) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288364-A | REACTING A 3-/2-HYDROXYIMINOACETYLAMINO/-2-OXOAZETIDINE WITH AN ORGANIC CARBONATE OR ACYL HALIDE | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |