⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27990161 | 0.97 | — | — | |
| SCHEMBL193790 | 0.93 | — | — | |
| SCHEMBL421334 | 0.90 | — | — | |
| SCHEMBL29140631 | 0.89 | CXCR4 (0.40) | — | |
| SCHEMBL1699710 | 0.88 | — | — | |
| SCHEMBL7483946 | 0.88 | ALDH1A1 (0.53) | — | |
| SCHEMBL7478554 | 0.88 | ALDH1A1 (0.53) | — | |
| SCHEMBL28256963 | 0.87 | ALDH1A1 (0.41) | — | |
| SCHEMBL1699079 | 0.87 | — | — | |
| SCHEMBL8504 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2980 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| WO-2023107490-A1 | HETEROCYCLE-CONTAINING LONP1 INHIBITOR COMPOUNDS, USES AND METHODS | PRETZEL THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | claimed |
| EP-4028125-A1 | NOVEL QUINOLINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2022-07-20 | — | — | EP | claimed |
| EP-4008720-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVE USED AS TLR8 AGONIST | BeiGene, Ltd. (KY) | 2022-06-08 | — | — | EP | claimed |
| US-11331314-B2 | Amine substituted triazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-05-17 | — | — | US | claimed |
| CN-114423747-A | Novel quinoline compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-114206872-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR8 agonists | 百济神州有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-108290838-B | Biaryl derivatives and drugs containing the same | 科研制药株式会社 | 2021-12-31 | — | — | CN | claimed |
| EP-3921319-A1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BeiGene, Ltd. (KY) | 2021-12-15 | — | — | EP | claimed |
| CN-113423708-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-21 | — | — | CN | claimed |
| US-5977102-A | INHIBITORY EFFECT ON SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES OR EPIDERMAL GROWTH FACTOR; ANTITUMOR,-CARCINOGENIC, -METASTASIS,-PROLIFERATION AGENTS AND -INFLAMMATORY AGENTS; PSORIASIS; ANGIOGENESIS INHIBITORS; IMMUNOLOGY; | DR. KARL THOMAE GMBH (DE) | 1999-11-02 | — | — | US | claimed |
| US-5821240-A | ENZYME INHIBITORS, SIGNAL INHIBITORS FOR ANTIINFLAMMATORY AGENTS, ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS AND HORMONE INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1998-10-13 | — | — | US | claimed |
| US-5817651-A | ANALGESICS, RHEUMATIC DISEASES, ANTIINFLAMMATORY AGENTS | SANOFI (FR) | 1998-10-06 | — | — | US | claimed |
| EP-0806419-A1 | Benzoxazole derivatives as serotonin 5-HT3 receptor partial activator | MEIJI SEIKA KAISHA LTD. (JP) | 1997-11-12 | — | — | EP | claimed |
| CN-1079745-A | New 9-fluoro-7-oxo-7H-pyrido [1,2,3-d, e] [1,4] benzoxazine-6-carboxylic acids and ester thereof | BAYER AG (DE) | 1993-12-22 | — | — | CN | claimed |
| US-5225207-A | Complexes derived from platinum, their preparation and the pharmaceutical compositions which contain them | LABORATOIRE ROGER BELLON (FR) | 1993-07-06 | — | — | US | claimed |
| EP-0444451-A2 | 3-Arylcarbonyl-1H-indoles useful as therapeutic agents | STERLING WINTHROP INC. (US) | 1991-09-04 | — | — | EP | claimed |
| US-4841047-A | ANTIALLERGENS | AASTA PHARMA AG (DE) | 1989-06-20 | — | — | US | claimed |
| EP-0160391-A1 | Carbapenem derivatives and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1985-11-06 | — | — | EP | claimed |
| EP-0031885-B1 | BASIC ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | MERCK PATENT GmbH (DE) | 1984-06-27 | — | — | EP | claimed |