SCHEMBL6247125

SCHEMBL6247125

CCN(N)C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 6/20 0.46
ADH1C P00326 4/20 0.46
PHGDH O43175 2/20 0.34
SHBG P04278 1/20 0.33
ABCB11 O95342 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
AR P10275 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33
PDE4A P27815 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KCNH2 Q12809 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
ADH1B P00325 1/20 0.32
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18884375 0.97
Hydrochloric Acid SCHEMBL4660209 0.95 ADH1A (0.41) ADH1AADH1CPHGDHCYP2D6CYP1A2
SCHEMBL18884478 0.86
SCHEMBL460664 0.80 ADH1A (0.50) ADH1AADH1CPHGDHSHBGHRH4
SCHEMBL16334056 0.78 ADH1A (0.37) ADH1AADH1CPHGDHHRH4HRH3
SCHEMBL16949669 0.77 ADH1A (0.48) ADH1AADH1CCYP1A2
SCHEMBL2347728 0.77 ADH1A (0.42) ADH1AADH1CSIGMAR1CYP1A2
SCHEMBL3952910 0.75 ADH1A (0.41) ADH1AADH1CSIGMAR1CYP1A2
SCHEMBL7609404 0.73 ADH1A (0.43) ADH1AADH1CSIGMAR1CYP1A2
SCHEMBL9193281 0.73 ADH1A (0.43) ADH1AADH1CSIGMAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028604-A Preparation method of cyclohexyl piperazine 万华化学集团股份有限公司 2022-09-09 CN disclosed
EP-1560809-A1 CYCLOHEXYLUREA DERIVATIVES Grünenthal GmbH (DE) 2005-08-10 EP disclosed
WO-2004043909-A1 CYCLOHEXYLUREA DERIVATIVES Grünenthal GmbH (DE) 2004-05-27 WO disclosed
US-4173542-A Hydraulic fluid comprising a borate ester and corrosion inhibiting amounts of an oxyalkylated alicyclic amine SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1979-11-06 US disclosed