Sugi Predict

Sugi Predict / Compounds / SCHEMBL6247488

SCHEMBL6247488

SCHEMBL6247488

CC(=O)NC[C@H]1CN(c2ccc(OC[C@@H]3[C@H]4CN(C(=O)OC(C)(C)C)C[C@@H]34)c(F)c2)C(=O)O1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 6/20 0.55
▸ MAOB P27338 4/20 0.55
▸ PTGS1 P23219 2/20 0.55
▸ SDHA P31040 2/20 0.55
▸ LMNA P02545 1/20 0.55
▸ CALML3 P27482 1/20 0.55
▸ F10 P00742 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6258771 0.87 MAOA (0.45) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2108790 0.86 MAOA (0.55) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6197843 0.86 MAOA (0.58) MAOAMAOBPTGS1SDHALMNA
SCHEMBL9890819 0.86 MAOA (0.57) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2107169 0.83 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL9890818 0.83 MAOA (0.54) MAOAMAOBPTGS1SDHALMNA
SCHEMBL10033751 0.82 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5412018 0.82 MAOB (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL8577685 0.82 MAOB (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4634173 0.81 MAOA (0.60) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1594852-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES, LTD. (IN) 2005-11-16 — — EP claimed
WO-2004069816-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2004-08-19 — — WO claimed