SCHEMBL6247828

SCHEMBL6247828

CC(C)c1nc(N)nc(Cl)n1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.43
ADORA2A P29274 2/20 0.41
HSP90AA1 P07900 1/20 0.34
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
ADORA1 P30542 1/20 0.31
NFKB1 P19838 1/20 0.31
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12452318 0.84 ALDH1A1 (0.44) GAATDP1ALDH1A1ALOX15TSHR
SCHEMBL15994399 0.84 HRH4 (0.52) HRH4ADORA2AADORA1
SCHEMBL1086109 0.82 HSP90AA1 (0.33) HRH4HSP90AA1GAATDP1
SCHEMBL1425789 0.82 HRH4 (0.50) HRH4ADORA2AADORA1
SCHEMBL5131454 0.82 ALDH1A1 (0.50) GAATDP1ALDH1A1ALOX15TSHR
SCHEMBL27461814 0.79 HRH4 (0.35) HRH4HSP90AA1
Propazine SCHEMBL28178808 0.77 GAA (0.66) GAATDP1ALDH1A1
SCHEMBL22556877 0.76 ALDH1A1 (0.32) HSP90AA1ALDH1A1ALOX15TSHR
SCHEMBL7770550 0.73 HRH4 (0.44) HRH4ADORA2AHSP90AA1ALDH1A1ADORA1
SCHEMBL6551721 0.73 HRH4 (0.32) HRH4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848710-B1 2,4- DIAMINO-1,3,5-TRIAZINES, PROCESS FOR THE PRODUCTION THEREOF, AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE GMBH (DE) 2005-08-10 EP disclosed
CN-1157384-C 2,4-diamino-1,3,5-triazines, process for production, and use thereof as herbicides and plant growth regulators �ճ�˹��-����ũҵ��չ���޹�˾ 2004-07-14 CN disclosed
EP-0880509-B1 2,4-DIAMINO-1,3,5-TRIAZINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS BAYER CROPSCIENCE GMBH (DE) 2003-11-12 EP disclosed
US-6645916-B1 Pre- or postemergent herbicides for crops HOECHST SCHERING AGREVO GMBH (DE) 2003-11-11 US disclosed
CN-1126744-C 2,4-diamino-1,3,5-triazines, manufacture and use thereof as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 2003-11-05 CN disclosed
US-20030203820-A1 2,4-diamino-1,3,5-triazines, their preparation and their use as herbicides and plant growth regulators ZINDEL JURGEN (DE) 2003-10-30 US disclosed
EP-1222178-A1 ALKYL-AMINO-1,3,5-TRIAZINES AND THEIR USE AS HERBICIDES Aventis CropScience GmbH (DE) 2002-07-17 EP disclosed
CN-1306519-A Substituted 2, 4-diamino-1, 3, 5-triazines, process for their preparation and their use as herbicides and plant growth regulators AVENTIES CROPS SCIENCES GMBH (DE) 2001-08-01 CN disclosed
US-6239071-B1 DIAMINO-1,3,5-TRIAZINE COMPOUND HOECHT SCHERING AGREVO GMBH (DE) 2001-05-29 US disclosed
WO-2001027093-A1 ALKYL-AMINO-1,3,5-TRIAZINES AND THEIR USE AS HERBICIDES AVENTIS CROPSCIENCE GMBH (DE) 2001-04-19 WO disclosed
US-6071860-A FOR SELECTIVE CONTROL OF BROAD-LEAVED AND GRASS WEEDS IN CROPS OF USEFUL PLANTS HOECHST SCHERING AGREVO GMBH (DE) 2000-06-06 US disclosed
CN-1246851-A 2,4-diamino-1,3,5-triazines, manufacture and use thereof as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 2000-03-08 CN disclosed
WO-2000000480-A1 SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS AVENTIS CROPSCIENCE GMBH (DE) 2000-01-06 WO disclosed
CN-1210522-A 2, 4-diamino-1, 3, 5-triazines, their preparation and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1999-03-10 CN disclosed
EP-0880509-A1 2,4-DIAMINO-1,3,5-TRIAZINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1998-12-02 EP disclosed
CN-1194640-A 2,4-diamino-1,3,5-triazines, process for production, and use thereof as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1998-09-30 CN disclosed
EP-0848710-A1 2,4- DIAMINO-1,3,5-TRIAZINES, PROCESS FOR THE PRODUCTION THEREOF, AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1998-06-24 EP disclosed
WO-1997029095-A1 2,4-DIAMINO-1,3,5-TRIAZINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1997-08-14 WO disclosed
WO-1997008156-A1 2,4- DIAMINO-1,3,5-TRIAZINES, PROCESS FOR THE PRODUCTION THEREOF, AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1997-03-06 WO disclosed
CN-1108656-A N-azinyl-N'-(HET)arylsulphonyl-ureas BAYER AG (DE) 1995-09-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030203820-A1 2,4-diamino-1,3,5-triazines, their preparation and their use as herbicides and plant growth regulators DAZAP1, DDT, DCUN1D5 HRH4 1447/4885ADORA2A 1351/4885HSP90AA1 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.