SCHEMBL6248129

SCHEMBL6248129

Cc1cc2ccccc2s1.Cc1ccc2ccccc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 9/20 0.63
TDP1 Q9NUW8 1/20 0.63
CYP1A2 P05177 5/20 0.48
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
ALDH1A1 P00352 2/20 0.42
ADRB2 P07550 1/20 0.40
ASIC3 Q9UHC3 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
MGLL Q99685 1/20 0.39
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
BCL2L1 Q07817 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CA2 P00918 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12417 0.86 ALDH1A1 (0.52) CYP2A6CA12CA9ALDH1A1ADRB2
Ammonia Solution, Strong SCHEMBL28821949 0.84 CYP2A6 (0.52) CYP2A6CA12CA9ALDH1A1ADRB2
Hydrogen Sulfide SCHEMBL28032128 0.84 ALDH1A1 (0.50) CYP2A6CA12CA9ALDH1A1ADRB2
SCHEMBL422041 0.80 HDAC3 (0.52) CYP2A6TDP1CYP1A2ALDH1A1MAPT
SCHEMBL144441 0.80 CYP2A6 (0.57) CYP2A6TDP1CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL28081333 0.79 CYP2A6 (1.00) CYP2A6TDP1CYP1A2CA9ALDH1A1
SCHEMBL36453 0.79 CYP2A6 (1.00) CYP2A6TDP1CYP1A2CA9ALDH1A1
SCHEMBL29372904 0.79 CYP2A6 (1.00) CYP2A6TDP1CYP1A2CA9ALDH1A1
SCHEMBL14985718 0.78 CYP2A6 (0.48) CYP2A6TDP1CYP1A2CA12ALDH1A1
SCHEMBL13477886 0.77 APP (0.56) CYP2A6TDP1CYP1A2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005040308-A2 METHOD AND APPARATUS FOR CONVERTING AND REMOVING ORGANOSULFUR AND OTHER OXIDIZABLE COMPOUNDS FROM DISTILLATE FUELS, AND COMPOSITIONS OBTAINED THEREBY DEGUSSA CORPORATION (US) 2005-05-06 WO disclosed