Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 16/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6449479 | 0.94 | CCR8 (0.47) | CCR8KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL6411940 | 0.89 | CCR8 (0.59) | CCR8 | |
| SCHEMBL6415241 | 0.88 | CCR8 (0.55) | CCR8KDM4EALDH1A1MAPT | |
| SCHEMBL6203108 | 0.88 | CCR8 (0.47) | CCR8ALDH1A1 | |
| SCHEMBL6204086 | 0.86 | CCR8 (0.52) | CCR8 | |
| SCHEMBL6253417 | 0.83 | CCR8 (0.45) | CCR8 | |
| SCHEMBL6254437 | 0.82 | CCR8 (0.57) | CCR8 | |
| SCHEMBL6454690 | 0.82 | CCR8 (0.48) | CCR8ALDH1A1 | |
| SCHEMBL6204820 | 0.81 | CCR8 (0.60) | CCR8 | |
| SCHEMBL6416674 | 0.81 | CYP1A2 (0.43) | CCR8KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590327-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1581511-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058709-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058736-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |