Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 18/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.83 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936844 | 0.92 | OPRD1 (0.70) | OPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL12569814 | 0.92 | OPRD1 (0.80) | OPRD1KCNH2OPRM1 | |
| SCHEMBL12569816 | 0.92 | OPRD1 (0.80) | OPRD1KCNH2OPRM1 | |
| SCHEMBL1999217 | 0.92 | OPRD1 (0.80) | OPRD1KCNH2OPRM1 | |
| SCHEMBL2002716 | 0.88 | OPRD1 (0.71) | OPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL6266611 | 0.87 | OPRD1 (0.86) | OPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL5522686 | 0.86 | OPRD1 (0.65) | OPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL5522677 | 0.86 | OPRD1 (0.65) | OPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL1998734 | 0.85 | OPRD1 (0.65) | OPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL1998738 | 0.85 | OPRD1 (0.65) | OPRD1KCNH2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562924-A1 | 4(PHENYL-PIPERAZINYL-METHYL) BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS | AstraZeneca AB (SE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004041802-A1 | 4(PHENYL-PIPERAZINYL-METHYL) BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2004-05-21 | — | — | WO | claimed |