SCHEMBL6248684

SCHEMBL6248684

CCCCC=CC[SiH](I)I

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.41
TRPV1 Q8NER1 2/20 0.41
F7 P08709 2/20 0.40
F3 P13726 2/20 0.40
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TERT O14746 3/20 0.35
CYP1A2 P05177 2/20 0.35
MAPT P10636 2/20 0.35
CYP2C19 P33261 2/20 0.35
BLM P54132 2/20 0.35
HSD17B10 Q99714 2/20 0.35
FABP4 P15090 2/20 0.35
PTPN1 P18031 2/20 0.35
PPARG P37231 2/20 0.35
KMT2A Q03164 2/20 0.35
PPARD Q03181 2/20 0.35
PPARA Q07869 2/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21383174 0.80 FAAH (0.38) FAAHTRPV1F7F3TSHR
SCHEMBL9133779 0.80 FAAH (0.55) FAAHTRPV1F7F3TSHR
SCHEMBL9133782 0.80 FAAH (0.55) FAAHTRPV1F7F3TSHR
SCHEMBL17262056 0.80 FAAH (0.55) FAAHTRPV1F7F3TSHR
SCHEMBL93117 0.80 FAAH (0.55) FAAHTRPV1F7F3TSHR
SCHEMBL23566850 0.80 FAAH (0.55) FAAHTRPV1F7F3TSHR
SCHEMBL93116 0.80 FAAH (0.55) FAAHTRPV1F7F3TSHR
SCHEMBL27959796 0.78
SCHEMBL17725942 0.78
SCHEMBL15302788 0.77 FAAH (0.39) FAAHTRPV1F7F3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768732-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
EP-3768733-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
US-20210017311-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2021-01-21 US disclosed
US-20210017195-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-21 US disclosed
CN-111868110-A Silicon-terminated telechelic polyolefin compositions and methods of making the same 陶氏环球技术有限责任公司 2020-10-30 CN disclosed
WO-2019182993-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
WO-2019182992-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
EP-1125939-B1 Process for reducing the amount of linear siloxane in a mixture of linear and cyclic siloxanes DOW CORNING TORAY SILICONE (JP) 2005-08-10 EP disclosed
US-6448360-B2 USING BASIC CATALYST DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-09-10 US disclosed
EP-1125939-A1 Process for the production of cyclic siloxane Dow Corning Toray Silicone Co., Ltd. (JP) 2001-08-22 EP disclosed
US-20010011120-A1 Process for the production of cyclic siloxane DOW TORAY CO., LTD. (JP) 2001-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210017195-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY ZRANB2, NISCH, ZKSCAN2 FAAH 3349/4885TRPV1 2743/4885F7 2781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.