Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 19/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624007 | 0.87 | PIM1 (0.51) | PIM1KCNH2DYRK1A | |
| SCHEMBL624838 | 0.85 | PIM1 (0.48) | PIM1KCNH2DYRK1A | |
| SCHEMBL625502 | 0.82 | PIM1 (0.69) | PIM1KCNH2 | |
| Hydrochloric Acid SCHEMBL625022 | 0.82 | FYN (0.58) | PIM1KCNH2 | |
| SCHEMBL623848 | 0.79 | DYRK1A (0.47) | PIM1KCNH2DYRK1A | |
| SCHEMBL624032 | 0.78 | PIM1 (0.47) | PIM1KCNH2DYRK1A | |
| SCHEMBL1945251 | 0.78 | FYN (0.64) | PIM1KCNH2 | |
| SCHEMBL1945309 | 0.76 | FYN (0.71) | PIM1KCNH2 | |
| SCHEMBL625516 | 0.76 | PIM1 (0.57) | PIM1KCNH2DYRK1A | |
| SCHEMBL28944695 | 0.76 | DYRK1A (0.54) | PIM1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |