SCHEMBL6249367

SCHEMBL6249367

CC(=O)C(=O)O[C@H](C)[C@H](N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.46
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
CASR P41180 1/20 0.36
TSHR P16473 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3333899 0.83 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL3333900 0.83 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL28147764 0.83 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL3449733 0.82 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL678144 0.82 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL678145 0.82 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL28327923 0.79 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL4602194 0.79 SLC7A5 (0.39) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL4267130 0.78 SLC7A5 (0.41) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL5218767 0.77 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005047472-A2 INCREASING SEED THREONINE CONTENT THROUGH ALTERATION OF THREONINE ALDOLASE ACTIVITY BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH (US) 2005-05-26 WO disclosed